Regenerative & Anti-Aging Clinic
Service Description
Nucleofill® is an advanced polynucleotide treatment at Dr Diana Clinic in Nicosia, known for its strong bio-stimulating and firming action. Using highly purified polynucleotides, it stimulates the skin's natural regeneration while improving tone, elasticity and firmness — helping to counteract laxity and restore a fresher, more lifted appearance.
Rather than adding volume, Nucleofill® improves the quality and structure of the skin itself, gradually tightening and revitalising areas that have begun to lose firmness, for results that look natural.
What It Treats
- Mild to moderate skin laxity
- Loss of firmness and elasticity
- Dull, tired or crepey skin
- Overall skin tone and quality
DR. DIANA EXPLAINS
In Dr. Diana's Words
REAL RESULTS
Before & After
Who Is It Suitable For?
Ideal for those noticing early skin laxity or loss of firmness who want a natural, regenerative lift rather than added volume. A consultation confirms suitability and the most appropriate plan.
Recovery & Aftercare
Downtime is minimal. Mild redness or small bumps at the injection points may appear and usually settle within a day or two. Most people return to normal activities right away, following the simple aftercare advice provided at the clinic.
Frequency & Maintenance
An initial course of sessions spaced a few weeks apart is typically recommended for best results, followed by periodic maintenance tailored to you during consultation.
OFFICIAL VIDEO
Get to Know It
QUESTIONS
Frequently Asked
What is Nucleofill?
A polynucleotide treatment that stimulates skin regeneration with a strong firming and bio-stimulating effect, improving tone, elasticity and firmness.
How is it different from Plinest?
Nucleofill is known for a stronger firming and tightening action, while both stimulate the skin's natural regeneration. Your clinician advises which suits your goals.
Is there any downtime?
Downtime is minimal. Mild redness or small bumps may appear briefly and usually settle within a day or two.
How many sessions will I need?
An initial course spaced a few weeks apart is usually advised, tailored during your consultation.
When will I see results?
Firmness and skin quality improve gradually over the weeks following treatment.
Medically reviewed by Dr. Diana Vulcanescu, MD · MRCGP(int) · DipDerm · Last reviewed: October 2026